Chronic urticaria in children can be controlled effectively with updosing second-generation antihistamines

Updosing nonsedating antihistamines in patients with chronic spontaneous urticaria: a systematic review and meta-analysis.

There is a lack of large, randomized, double-blind studies that address antihistamine updosing for chronic spontaneous urticaria (CSU). The objective of this systematic review is to explore and analyse available data to provide clinical evidence for the efficacy of antihistamine updosing. We searched the literature in Medline, Scopus, Google Scholar, Embase, Web of Science and Cochrane database...

Antihistamines in the treatment of chronic urticaria.

Chronic urticaria is highly prevalent in the general population, and while there are multiple treatments for the disorder, the results obtained are not completely satisfactory. The second-generation H1 antihistamines remain the symptomatic treatment option of choice. Depending on the different pharmacokinetics and H1 receptor affinity of each drug substance, different concentrations in skin can...

Antihistamines in chronic urticaria: threat or treat?

Can patient flow be effectively controlled?

BACKGROUND Emergency department (ED) overcrowding may affect the ability to provide quality care and maximize patient flow. Study objectives To analyse the impact of the control of the patient flow during a conflict on ED overcrowding. METHODS During a recent military conflict in Israel the Ministry of Health issued a directive aimed at redirecting the patient flow to EDs in a metropolitan are...

Antihistamines in Recalcitrant Urticaria

Nonsedating antihistamines are the fi rst-choice treatment for all forms of urticaria. In patients with recalcitrant urticaria who do not respond to conventional doses of antihistamines, current guidelines recommend increasing doses by up to 4 times in order to obtain better control of the disease. Although few studies have been conducted, there are convincing data from controlled trials for ce...